
dbSNP: databáze NCBI genetických variací.
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dbSNP: databáze NCBI genetických variací.
In response to a necessity for a standard catalog of genome variation to cope with the large-scale sampling designs required by affiliation analysis, gene mapping and evolutionary biology, the Nationwide Coronary heart for Biotechnology Knowledge (NCBI) has established the dbSNP database [S.T.Sherry, M.Ward and K. Sirotkin (1999) Genome Res., 9, 677-679]. Submissions to dbSNP may be built-in with completely different sources of data at NCBI harking back to GenBank, PubMed, LocusLink and the Human Genome Endeavor info.

PI |
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PI | ImmunoStep | 400 test | EUR 184.8 |
PI/RNAse |
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PI/RNASE | ImmunoStep | 200 test | EUR 208.2 |
50 ML AMPHOTERICIN B, LIQUID 250 µG/ML SOLUBILIZED |
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30-003-CF | CORNING | 50 mL/pk | EUR 97.2 |
Description: Media Catalog; Cell Culture Reagents |
50 ML KANAMYCIN SULFATE, LIQUID, 5,000 µG/ML SOLUTION |
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30-006-CF | CORNING | 50 mL/pk | EUR 117.6 |
Description: Media Catalog; Cell Culture Reagents |
Human Proinsulin (PI) ELISA Kit |
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DLR-PI-Hu-48T | DL Develop | 48T | EUR 574.8 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Proinsulin (PI) ELISA Kit |
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DLR-PI-Hu-96T | DL Develop | 96T | EUR 745.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Porcine Proinsulin (PI) ELISA Kit |
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DLR-PI-p-48T | DL Develop | 48T | EUR 656.4 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Porcine Proinsulin (PI) ELISA Kit |
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DLR-PI-p-96T | DL Develop | 96T | EUR 858 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Proinsulin (PI) ELISA Kit |
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RD-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 573.6 |
Human Proinsulin (PI) ELISA Kit |
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RD-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 794.4 |
Porcine Proinsulin (PI) ELISA Kit |
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RD-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 666 |
Porcine Proinsulin (PI) ELISA Kit |
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RD-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 925.2 |
Human Proinsulin (PI) ELISA Kit |
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RDR-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 600 |
Human Proinsulin (PI) ELISA Kit |
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RDR-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 830.4 |
Porcine Proinsulin (PI) ELISA Kit |
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RDR-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 696 |
Porcine Proinsulin (PI) ELISA Kit |
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RDR-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 968.4 |
Amphotericin B (Fungizone) Sol, 250 µg/mL |
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CCM1120-100 | Bio Basic | 100 mL | EUR 132.28 |
Fluorguard Antifade Mounting Medium |
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F001 | Insitus Biotechnologies | 1 ml | EUR 103.2 |
Latex-in-a-Box Conjugation Kit, Blue 0.3 micron, 7 mL |
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LIB03-B007 | BioAssayWorks | 7 mL | EUR 880.73 |
Description: Latex-in-a-Box Conjugation Kit conjugates blue 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
Latex-in-a-Box Conjugation Kit, Red 0.3 micron, 7 mL |
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LIB03-R007 | BioAssayWorks | 7 mL | EUR 880.73 |
Description: Latex-in-a-Box Conjugation Kit conjugates red 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
Penicillin-Streptomycin 100X Solution, 10, 000 Units/mL, 10, 000 µg/mL |
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CCM1133-100 | Bio Basic | 100 mL | EUR 76.86 |
Starch Indicator 0.3% |
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ST0305 | Scientific Laboratory Supplies | 500ML | EUR 93.48 |
Pi-minimal Screen HTS (1.7 ml per well) |
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M-CS-211L | MiTeGen | 96 solutions | EUR 508 |
Description: Pi-minimal Screen HTS (1.7 ml per well) |
Pi-PEG Screen HTS (1.7 ml per well) |
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M-CS-212L | MiTeGen | 96 solutions | EUR 508 |
Description: Pi-PEG Screen HTS (1.7 ml per well) |
100 ML PENICILLIN-STREPTOMYCIN-L-GLUTAMINE, 100X, 10,000 I.U. PENCILLIN (PER ML) 10,000 µG/ML STREPTOMYCIN 29.2 MG/ML L-GLUTAMINE |
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30-009-CI | CORNING | 100 mL/pk | EUR 96 |
Description: Media Catalog; Cell Culture Reagents |
PI |
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abx290031-400tests | Abbexa | 400 tests | EUR 309.6 |
pI |
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EF007077 | Lifescience Market | 96 Tests | EUR 826.8 |
PI/ Rat PI ELISA Kit |
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ELA-E0379r | Lifescience Market | 96 Tests | EUR 1063.2 |
Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes (2 x 0.3 mL) |
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0801384 | Zeptometrix | 2 x 0.3 mL | EUR 396.96 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA3800 | ScyTek Laboratories | 1 Gal. | EUR 289.2 |
Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA500 | ScyTek Laboratories | 500 ml | EUR 108 |
Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA999 | ScyTek Laboratories | 1000 ml | EUR 139.2 |
Hydrogen Peroxide 0.3% w/v |
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HP035 | Scientific Laboratory Supplies | 5L | EUR 120.84 |
Hydrogen Peroxide 0.3% w/v |
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HP03F | Scientific Laboratory Supplies | 1L | EUR 43.32 |
Random Hexamers 100 µg |
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26-4000-03 | Gene Link | 100 ug | EUR 150 |
Description: Random Primers are a mixture of oligonucleotides representing all possible sequence for that size. Random Primers can be used to prime synthesis in oligo-labeling similar to using hexamers (1,2) and cDNA synthesis. Random prime labeling yields high specific activity labeled DNA probe which can be used for all southern, northern and in situ hybridization studies. Random Primers can be also used similar to using hexamers in cDNA synthesis in combination with oligo d(T) to yield more 5' end cDNA sequence. Recently random primers have been used to detect DNA polymorphism. These polymorphisms, simply detected as DNA segments which amplify from one parent but not the other, are inherited in a Mendelian fashion and can be used to construct genetic maps in a variety of species. The authors suggested that these polymorphisms be called RAPD (pronounced RAPID) makers, after Random Amplified Polymorphic DNA (3). References 1. Feinberg, A.P. & Vogelstein, B. (1983) Anal. Biochem. 132:6-13. 2. Feinberg, A.P. & Vogelstein, B. (1984) Anal. Biochem. 137:266-267. 3. Williams J. G., Kubelik A.R., Livak K.J., Rafalski J.A. & Tingey S.V. (1990) Nucleic Acid Res. 18(22):6531-5. |
0.3 ml 8-Strip Tubes & Domed Caps, 250 Strips of 8 Tubes and Caps |
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GP209 | GenDepot | 2,000 tubes/caps | EUR 400.8 |
PI-103 |
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E1KS1038 | EnoGene | 5mg | EUR 390 |
PI-103 |
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1728-1 | Biovision | EUR 183.6 |
PI-103 |
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1728-5 | Biovision | EUR 502.8 |
PI-103 |
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1728-50 | Biovision | Ask for price |
PI-103 |
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A2067-100 | ApexBio | 100 mg | EUR 1005.6 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
PI-103 |
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A2067-25 | ApexBio | 25 mg | EUR 393.6 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
PI-103 |
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A2067-5 | ApexBio | 5 mg | EUR 176.4 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
PI-103 |
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A2067-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 184.8 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
PI-103 |
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A2067-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
PI / RNAse |
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abx290029-200tests | Abbexa | 200 tests | EUR 326.4 |
PI-3065 |
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B4660-10 | ApexBio | 10 mg | EUR 268.8 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
PI-3065 |
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B4660-100 | ApexBio | 100 mg | EUR 950.4 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
PI-3065 |
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B4660-5 | ApexBio | 5 mg | EUR 199.2 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
PI-3065 |
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B4660-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 212.4 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
PI-3065 |
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B4660-50 | ApexBio | 50 mg | EUR 686.4 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
PI-1840 |
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B4755-10 | ApexBio | 10 mg | EUR 220.8 |
Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
PI-1840 |
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B4755-50 | ApexBio | 50 mg | EUR 626.4 |
Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
PI-3065 |
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B1674-25 | Biovision | EUR 607.2 |
PI-3065 |
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B1674-5 | Biovision | EUR 189.6 |
PI 828 |
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B7198-1 | ApexBio | 1 mg | EUR 151.2 |
PI 828 |
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B7198-10 | ApexBio | 10 mg | EUR 381.6 |
PI 828 |
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B7198-5 | ApexBio | 5 mg | EUR 243.6 |
PI-828 |
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HY-108606 | MedChemExpress | 1mg | EUR 170.4 |
PI-3065 |
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HY-12235 | MedChemExpress | 10mM/1mL | EUR 244.8 |
PI-1840 |
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HY-12286 | MedChemExpress | 50mg | EUR 704.4 |
PI-103 |
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HY-10115 | MedChemExpress | 100mg | EUR 655.2 |
DiagPoly Amine Polystyrene Particles, 0.3 µm |
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DNM-F002 | Creative Diagnostics | 10 mL | EUR 696 |
Glutathione S-Transferase Pi (GST pi) Antibody |
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abx020559-10ug | Abbexa | 10 ug | EUR 410.4 |
In Situ Plate Seals, 10 seals |
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ML-CDSF1-10 | MiTeGen | 10 SEALS | EUR 160 |
Description: In Situ Plate Seals, 10 seals |
Modular In Situ-1 96 Well Crystallization Plate |
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ML-MIS-FP3D | MiTeGen | 1 PLATE | EUR 392 |
Description: Modular In Situ-1 96 Well Crystallization Plate |
PI-8 antibody |
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70R-12052 | Fitzgerald | 100 ug | EUR 470.4 |
Description: Rabbit polyclonal PI-8 antibody |
PI-8 Antibody |
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3748-100 | Biovision | EUR 379.2 |
PI-8 Antibody |
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3748-30T | Biovision | EUR 175.2 |
PI Staining Kit |
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abx097208-1Kit | Abbexa | 1 Kit | EUR 276 |
PI-103 Hydrochloride |
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A3724-100 | ApexBio | 100 mg | EUR 1005.6 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
PI-103 Hydrochloride |
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A3724-25 | ApexBio | 25 mg | EUR 393.6 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
PI-103 Hydrochloride |
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A3724-5 | ApexBio | 5 mg | EUR 176.4 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
PI-103 Hydrochloride |
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A3724-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 184.8 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
Human PI Protein |
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20-abx650990 | Abbexa |
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Phosphatidylinositol (PI) Antibody |
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20-abx179006 | Abbexa |
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Pi-Methylimidazoleacetic acid |
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HY-113274 | MedChemExpress | 5mg | EUR 224.4 |
PI-103 (Hydrochloride) |
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HY-10115A | MedChemExpress | 5mg | EUR 142.8 |
Recombinant Proinsulin (PI) |
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4-RPA379Hu01 | Cloud-Clone |
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Description: Recombinant Human Proinsulin expressed in: E.coli |
Pi-minimal Screen |
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M-CS-127 | MiTeGen | 4 x 24 solutions | EUR 1109 |
Description: Pi-minimal Screen |
Pi-PEG Screen |
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M-CS-128 | MiTeGen | 4 x 24 solutions | EUR 1109 |
Description: Pi-PEG Screen |
Anti-Pichia pastoris HCP |
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PI-49 | Cygnus Technologies | 1 ml | EUR 400.8 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
Anti-Pichia pastoris HCP |
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PI-49AF | Cygnus Technologies | 1 mg | EUR 2295.6 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
Anti-Pichia pastoris HCP |
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PI-49PA | Cygnus Technologies | 1 ml | EUR 585.6 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
DiagPoly Plain Polystyrene Particles, 0.2-0.3 µm |
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DNM-P003 | Creative Diagnostics | 10 mL | EUR 664.8 |
Anti-PON1 Clone KRJ1 (100 µg) |
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0801012 | Zeptometrix | 100 µg | EUR 340.8 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
Anti-PON1 Clone KRJ2 (100 µg) |
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0801014 | Zeptometrix | 100 µg | EUR 340.8 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
bFGF-nAb Purified Protein 25 µg |
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ABP-NAB-BFGFAB | Allele Biotech | 25 µg | Ask for price |
bFGF-nAb Plus Biotinylated 25 µg |
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ABP-NAB-BFGFPB | Allele Biotech | 25 µg | Ask for price |
GFP-nAb Purified Protein 25 µg |
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ABP-NAB-GFPAB | Allele Biotech | 25 µg | Ask for price |
GFP-nAb Plus Biotinylated 25 µg |
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ABP-NAB-GFPPB | Allele Biotech | 25 µg | Ask for price |
mNeonGreen-nAb Purified Protein 25 µg |
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ABP-NAB-MNGAB | Allele Biotech | 25 µg | Ask for price |
mNeonGreen-nAb Plus Biotinylated 25 µg |
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ABP-NAB-MNGPB | Allele Biotech | 25 µg | Ask for price |
RFP-nAb Purified Protein 25 µg |
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ABP-NAB-RFPAB | Allele Biotech | 25 ug | Ask for price |
RFP-nAb Plus Biotinylated 25 µg |
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ABP-NAB-RFPPB | Allele Biotech | 25 µg | Ask for price |
Rabbit Anti-Rat Glutathione Transferees pi (GST-pi) antiserum |
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GSTP11-S | Alpha Diagnostics | 100 ul | EUR 548.4 |
Rabbit Anti-Human Glutathione Transferase Pi (GST-pi) antiserum |
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GSTP12-S | Alpha Diagnostics | 100 ul | EUR 548.4 |
BrightGreen miRNA qPCR MasterMix-Low ROX |
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MasterMix-mL | ABM | 4 x 1.25 ml for 500 reactions | EUR 181.2 |
Rat Monoclonal Anti-Mouse CD4 Pur. Low Endotoxin (Clone YTS 191.1) (rat IgG2b) |
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MCD004-ML | Alpha Diagnostics | 100 ug | EUR 489.6 |
Rat Monoclonal Anti-Mouse CD25 , Pur. Low Endotoxin (Clone PC61.5.3) (rat IgG1) |
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MCD025-ML | Alpha Diagnostics | 100 ug | EUR 489.6 |
Vylepšené monomerní červené, oranžové a žluté fluorescenční proteiny odvozené od Discosoma sp. červený fluorescenční protein.
Fluorescent proteins are genetically encoded, merely imaged reporters important in biology and biotechnology. When a protein is tagged by fusion to a fluorescent protein, interactions between fluorescent proteins can undesirably disturb specializing in or function. Sadly, all wild-type yellow-to-red fluorescent proteins reported to this point are obligately tetrameric and typically toxic or disruptive. The first true monomer was mRFP1, derived from the Discosoma sp. fluorescent protein “DsRed” by directed evolution first to increase the tempo of maturation, then to interrupt each subunit interface whereas restoring fluorescence, which cumulatively required 33 substitutions.
Although mRFP1 has already confirmed broadly useful, various properties may bear enchancment and further colors may very well be welcome. We report the next period of monomers. The latest crimson mannequin matures additional absolutely, is additional tolerant of N-terminal fusions and is over tenfold additional photostable than mRFP1. Three monomers with distinguishable hues from yellow-orange to red-orange have bigger quantum efficiencies.
Chamtivý algoritmus skilled srovnávání sekvencí DNA.
For aligning DNA sequences that differ solely by sequencing errors, or by equal errors from completely different sources, a greedy algorithm could also be quite a bit before standard dynamic programming approaches and however produce an alignment that is assured to be theoretically optimum. We introduce a model new greedy alignment algorithm with notably good effectivity and current that it computes the an identical alignment as does a certain dynamic programming algorithm, whereas executing over 10 cases sooner on relevant info. An implementation of this algorithm is presently utilized in a program that assembles the UniGene database on the Nationwide Coronary heart for Biotechnology Knowledge.
Vývoj a aplikace CRISPR-Cas9 skilled genomové inženýrství.
Newest advances in genome engineering utilized sciences based totally on the CRISPR-associated RNA-guided endonuclease Cas9 are enabling the systematic interrogation of mammalian genome function. Analogous to the search function in fashionable phrase processors, Cas9 could also be guided to explicit areas inside sophisticated genomes by a short RNA search string. Using this system, DNA sequences all through the endogenous genome and their purposeful outputs in the meanwhile are merely edited or modulated in practically any organism of different.
Cas9-mediated genetic perturbation is straightforward and scalable, empowering researchers to elucidate the purposeful group of the genome on the methods diploma and arrange causal linkages between genetic variations and natural phenotypes. On this Consider, we describe the occasion and features of Cas9 for a variety of study or translational features whereas highlighting challenges along with future directions. Derived from a excellent microbial safety system, Cas9 is driving progressive features from basic biology to biotechnology and medicines.
Vylepšená Greengenesova taxonomie s explicitními hodnotami skilled ekologické a evoluční analýzy bakterií a archea.
- Reference phylogenies are important for providing a taxonomic framework for interpretation of marker gene and metagenomic surveys, which proceed to reveal novel species at a excellent cost. Greengenes is a loyal full-length 16S rRNA gene database that provides prospects with a curated taxonomy based totally on de novo tree inference.
- We developed a ‘taxonomy to tree’ methodology for transferring group names from an present taxonomy to a tree topology, and used it to make use of the Greengenes, Nationwide Coronary heart for Biotechnology Knowledge (NCBI) and cyanoDB (Cyanobacteria solely) taxonomies to a de novo tree comprising 408,315 sequences. We moreover included categorical rank information provided by the NCBI taxonomy to group names (by prefixing rank designations) for greater particular person orientation and classification consistency.
- The following merged taxonomy improved the classification of 75% of the sequences by various ranks relative to the distinctive NCBI taxonomy with the most pronounced enhancements occurring in under-classified environmental sequences. We moreover assessed candidate phyla (divisions) presently outlined by NCBI and present solutions for consolidation of 34 redundantly named groups.
- All intermediate outcomes from the pipeline, which contains tree inference, jackknifing and swap of a donor taxonomy to a recipient tree (tax2tree) could be discovered for get hold of. The improved Greengenes taxonomy must current very important infrastructure for a wide range of megasequencing initiatives discovering out ecosystems on scales ranging from our private our our bodies (the Human Microbiome Endeavor) to the whole planet (the Earth Microbiome Endeavor).
Molekulární chaperony v cytosolu: od rodícího se řetězce po skládaný protein.
Setting pleasant folding of many newly synthesized proteins relies upon upon assist from molecular chaperones, which serve to cease protein misfolding and aggregation inside the crowded ambiance of the cell. Nascent chain–binding chaperones, along with set off situation, Hsp70, and prefoldin, stabilize elongating chains on ribosomes in a nonaggregated state.
Folding inside the cytosol is achieved each on managed chain launch from these components or after swap of newly synthesized proteins to downstream chaperones, such as a result of the chaperonins. These are large, cylindrical complexes that current a central compartment for a single protein chain to fold unimpaired by aggregation. Understanding how the 1000’s of varied proteins synthesized in a cell use this chaperone tools has profound implications for biotechnology and medicines.
Konstrukce genetického přepínače v Escherichia coli.
It has been proposed’ that gene-regulatory circuits with practically any desired property could also be constructed from networks of easy regulatory components. These properties, which embody multistability and oscillations, have been current in specialised gene circuits such as a result of the bacteriophage lambda change and the Cyanobacteria circadian oscillator. However, these behaviours have not been demonstrated in networks of non-specialized regulatory components. Proper right here we present the event of a genetic toggle switch-a synthetic, bistable gene-regulatory network-in Escherichia coli and provide a straightforward precept that predicts the circumstances compulsory for bistability.
The toggle is constructed from any two repressible promoters organized in a mutually inhibitory neighborhood. It is flipped between regular states using transient chemical or thermal induction and shows an virtually supreme switching threshold. As a wise system, the toggle change sorts a synthetic, addressable cellular memory unit and has implications for biotechnology, biocomputing and gene treatment.
Aqueous Mounting Medium |
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AR1018 | BosterBio | 10mL X5 (Enough for 800-1200 assays) | EUR 96 |
Antifade Mounting Medium |
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AR1109 | BosterBio | 10mL (for 1000 assays) | EUR 78 |
Fluorguard Antifade Mounting Medium |
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F001 | Insitus Biotechnologies | 1 ml | EUR 103.2 |
EverBrite Hardset Mounting Medium |
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23003 | Biotium | 10mL | EUR 234 |
Description: Minimum order quantity: 1 unit of 10mL |
Anti-Fade Mounting Medium |
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abx090692-10ml | Abbexa | 10 ml | EUR 243.6 |
FluoreGuard Mounting Medium (Hard Set) |
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FMH030 | ScyTek Laboratories | 30 ml | EUR 115.2 |
FluoreGuard Mounting Medium (Hard Set) |
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FMH060 | ScyTek Laboratories | 60 ml | EUR 139.2 |
FluoreGuard Mounting Medium (Hard Set) |
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FMH500 | ScyTek Laboratories | 500 ml | EUR 392.4 |
FluoreGuard Mounting Medium (Hard Set) |
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FMH999 | ScyTek Laboratories | 1000 ml | EUR 636 |
EverBrite Hardset Mounting Medium with DAPI |
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23004 | Biotium | 10mL | EUR 255.6 |
Description: Minimum order quantity: 1 unit of 10mL |
FluoroQuest™ Mounting Medium with DAPI |
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20004 | AAT Bioquest | 50 mL | EUR 158.4 |
Anti-Fade Mounting Medium (With DAPI) |
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abx090690-10ml | Abbexa | 10 ml | EUR 243.6 |
Anti-Fade Mounting Medium (With PI) |
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abx090691-10ml | Abbexa | 10 ml | EUR 243.6 |
FluoroQuest™ Anti-fading Mounting Medium with DAPI |
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20005 | AAT Bioquest | 20 mL | EUR 211 |
Mounting Media |
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99-MED | Fitzgerald | 3 ml | EUR 253.2 |
Description: Mounting media for use in microscopy preparations |
FluorLast? Mounting Media |
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1213-20 | Biovision | EUR 170.4 |
MILLIPAK MOUNTING KITT |
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MPKMNTKIT | Scientific Laboratory Supplies | EACH | EUR 189.24 |
Wall Mounting Kit |
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WAT2452 | Scientific Laboratory Supplies | EACH | EUR 123.12 |
Wall Mounting Kit |
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WAT2456 | Scientific Laboratory Supplies | EACH | EUR 229.14 |
WALL MOUNTING BRACKET |
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WMBSMT002 | Scientific Laboratory Supplies | EACH | EUR 157.32 |
Buffered Glycerol Mounting Media |
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GMM003 | ScyTek Laboratories | 3 ml | EUR 73.2 |
Buffered Glycerol Mounting Media |
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GMM030 | ScyTek Laboratories | 30 ml | EUR 86.4 |
Buffered Glycerol Mounting Media |
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GMM500 | ScyTek Laboratories | 500 ml | EUR 219.6 |
Buffered Glycerol Mounting Media |
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GMM999 | ScyTek Laboratories | 1000 ml | EUR 312 |
Permanent Mounting Media (Aqueous) |
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PMT030 | ScyTek Laboratories | 30 ml | EUR 130.8 |
Permanent Mounting Media (Aqueous) |
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PMT999 | ScyTek Laboratories | 1000 ml | EUR 910.8 |
OPTICAP WALL MOUNTING BRACKET |
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M0PMNTKIT | Scientific Laboratory Supplies | EACH | EUR 149.34 |
Wall Mounting Kit (TANK30) |
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WAT2448 | Scientific Laboratory Supplies | EACH | EUR 115.14 |
Wall Mounting Kit (TANK60) |
|||
WAT2450 | Scientific Laboratory Supplies | EACH | EUR 119.7 |
Elga Wall Mounting Kit |
|||
WAT4044 | Scientific Laboratory Supplies | EACH | EUR 335.16 |
Elga Wall Mounting Kit |
|||
WAT4046 | Scientific Laboratory Supplies | EACH | EUR 132.24 |
WALL MOUNTING BRACKET (1) |
|||
SYSTFIX01 | Scientific Laboratory Supplies | EACH | EUR 287.28 |
WALL MOUNTING BRACKET TANKPE100 |
|||
TANKFIXS1 | Scientific Laboratory Supplies | EACH | EUR 587.1 |
ReadiUse™ microscope mounting solution |
|||
20009 | AAT Bioquest | 50 mL | EUR 138 |
Mounting Bracket For Base MIC2510 |
|||
MIC2510 | Scientific Laboratory Supplies | EACH | EUR 79.8 |
Elga Flex Wall Mounting Kit |
|||
WAT4170 | Scientific Laboratory Supplies | EACH | EUR 406.98 |
WALL MOUNTING BRACKET W VALVE |
|||
WMBSMT001 | Scientific Laboratory Supplies | EACH | EUR 207.48 |
WALL MOUNTING BRACKET (1/P) |
|||
TANKFIX01 | Scientific Laboratory Supplies | EACH | EUR 178.98 |
MicroRT room temperature mounting kit |
|||
RT-T1 | MiTeGen | 1 KIT | EUR 64 |
Description: MicroRT room temperature mounting kit20 MicroRT tubes, razor blade and grease tube |
Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 60ml |
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NB300 | Innovex | 60 ml | EUR 512.4 |
Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 30ml |
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NB300-30 | Innovex | 30 ml | EUR 331.2 |
Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 125ml |
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NB300A | Innovex | 125 ml | EUR 651.6 |
PolyMount Mounting Media MaxTag Histo (OKRA00045) |
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OKRA00045 | Aviva Systems Biology | 15 ml | EUR 151.2 |
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
KL 300 LED Column Mounting Bracket |
|||
MIC2528 | Scientific Laboratory Supplies | EACH | EUR 58.14 |
Holder for water tank for mounting |
|||
CHA4068 | Scientific Laboratory Supplies | EACH | EUR 108.3 |
WALL MOUNTING BRACKET WASHER PUMP KIT |
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WMBWASH1 | Scientific Laboratory Supplies | EACH | EUR 137.94 |
Fine natural hair brush for mounting sections |
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PO501 | FD Neurotechnologies | each | EUR 80.4 |
A Medium |
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DJ1018 | Bio Basic | 100g | EUR 101.76 |
DC MEDIUM |
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D04-117-10kg | Alphabiosciences | 10 kg | EUR 1894.8 |
DC MEDIUM |
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D04-117-2kg | Alphabiosciences | 2kg | EUR 458.4 |
DC MEDIUM |
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D04-117-500g | Alphabiosciences | 500 g | EUR 168 |
Advanced Medium |
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C0003-04 | Addexbio | RT 500 mL Bottle | EUR 123.6 |
Medium 199 |
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C0012-01 | Addexbio | RT 500 mL Bottle | EUR 126 |
COLIFORM MEDIUM |
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C03-127-10kg | Alphabiosciences | 10 kg | EUR 1588.8 |
COLIFORM MEDIUM |
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C03-127-2kg | Alphabiosciences | 2kg | EUR 392.4 |
COLIFORM MEDIUM |
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C03-127-500g | Alphabiosciences | 500 g | EUR 150 |
Heller's Medium |
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CP014-010 | GenDepot | 10X1L | EUR 118.8 |
Heller's Medium |
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CP014-500 | GenDepot | 50L | EUR 151.2 |
Hoagland's Medium |
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CP015-010 | GenDepot | 10X1L | EUR 118.8 |
Hoagland's Medium |
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CP015-500 | GenDepot | 50L | EUR 151.2 |
EC MEDIUM |
|||
E05-100-10kg | Alphabiosciences | 10 kg | EUR 976.8 |
EC MEDIUM |
|||
E05-100-2Kg | Alphabiosciences | 2 Kg | EUR 259.2 |
EC MEDIUM |
|||
E05-100-500g | Alphabiosciences | 500 g | EUR 114 |
NeuroProgenitor Medium |
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NM42400 | Neuromics | 125 ml | EUR 364.8 |
HLP MEDIUM |
|||
H08-107-10kg | Alphabiosciences | 10 kg | EUR 2733.6 |
HLP MEDIUM |
|||
H08-107-2Kg | Alphabiosciences | 2 Kg | EUR 640.8 |
HLP MEDIUM |
|||
H08-107-500g | Alphabiosciences | 500 g | EUR 218.4 |
SIM MEDIUM |
|||
S19-110-10kg | Alphabiosciences | 10 kg | EUR 1225.2 |
SIM MEDIUM |
|||
S19-110-2kg | Alphabiosciences | 2kg | EUR 313.2 |
SIM MEDIUM |
|||
S19-110-500g | Alphabiosciences | 500 g | EUR 128.4 |
SOB MEDIUM |
|||
S19-124-10kg | Alphabiosciences | 10 kg | EUR 1158 |
SOB MEDIUM |
|||
S19-124-2kg | Alphabiosciences | 2kg | EUR 298.8 |
SOB MEDIUM |
|||
S19-124-500g | Alphabiosciences | 500 g | EUR 124.8 |
M9 Medium |
|||
SD7024 | Bio Basic | 250g | EUR 86.1 |
M9CA Medium |
|||
SD7025 | Bio Basic | 250g | EUR 86.1 |
YM Medium |
|||
SD7031 | Bio Basic | 250g | EUR 84.54 |
TYGPN Medium |
|||
SD7032 | Bio Basic | 250g | EUR 84.01 |
M63 Medium |
|||
SD7033 | Bio Basic | 250g | EUR 86.1 |
TCBS Medium |
|||
MED1188 | Scientific Laboratory Supplies | PK10 | EUR 7.52 |
DNase Medium |
|||
MED1196 | Scientific Laboratory Supplies | PK10 | EUR 7.98 |
OF Medium |
|||
MED1664 | Scientific Laboratory Supplies | 500G | EUR 68.4 |
Probe Mount, Permanent Mounting media for permanent mounting and coverslipping of Special stainsd & Immunofluorescence and In-Situ Stains 60ml |
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NB316 | Innovex | 60 ml | EUR 582 |
Insect Cell Medium: TNM-FH Insect Culture Medium |
|||
ABP-MED-10001 | Allele Biotech | 1 liter | Ask for price |
Insect Cell Medium: Serum-Free Insect Culture Medium |
|||
ABP-MED-10002 | Allele Biotech | 1 liter | Ask for price |
Insect Cell Medium: Grace?s Insect Medium (Unsupplemented) |
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ABP-MED-10004 | Allele Biotech | 1 liter | Ask for price |
MCDB 131 Medium |
|||
CM034-050 | GenDepot | 500ml | EUR 102 |
MCDB 131 Medium |
|||
CM034-300 | GenDepot | 6x500ml | EUR 198 |
MCDB 131 Medium |
|||
CM034-310 | GenDepot | 10x500ml | EUR 262.8 |
MCDB 131 Medium |
|||
CM034-320 | GenDepot | 20x500ml | EUR 408 |
MCDB 131 Medium |
|||
CM034-350 | GenDepot | 50x500ml | EUR 702 |
Williams' Medium E |
|||
CM063-050 | GenDepot | 500ml | EUR 109.2 |
Williams' Medium E |
|||
CM063-300 | GenDepot | 6x500ml | EUR 319.2 |
Williams' Medium E |
|||
CM063-310 | GenDepot | 10x500ml | EUR 375.6 |
Williams' Medium E |
|||
CM063-320 | GenDepot | 20x500ml | EUR 724.8 |
Williams' Medium E |
|||
CM063-350 | GenDepot | 50x500ml | EUR 1170 |
H Medium Broth |
|||
DJ1019 | Bio Basic | 100g | EUR 73.06 |
AddexBio Cryopreservation Medium |
|||
C0002-20mL | Addexbio | RT vial | EUR 124.8 |
CARY & BLAIR MEDIUM |
|||
C03-131-10kg | Alphabiosciences | 10 kg | EUR 2622 |
CARY & BLAIR MEDIUM |
|||
C03-131-2Kg | Alphabiosciences | 2 Kg | EUR 616.8 |
CARY & BLAIR MEDIUM |
|||
C03-131-500g | Alphabiosciences | 500 g | EUR 211.2 |
Cereal Crops Medium |
|||
CP003-005 | GenDepot | 5L | EUR 135.6 |
Cereal Crops Medium |
|||
CP003-010 | GenDepot | 10X1L | EUR 202.8 |
Kao Michayluk Medium |
|||
CP017-010 | GenDepot | 10X1L | EUR 118.8 |
Kao Michayluk Medium |
|||
CP017-500 | GenDepot | 50L | EUR 151.2 |
Orchid Maintenance Medium |
|||
CP037-010 | GenDepot | 10X1L | EUR 130.8 |
Orchid Maintenance Medium |
|||
CP037-500 | GenDepot | 50L | EUR 165.6 |
Woody Plants Medium |
|||
CP040-010 | GenDepot | 10X1L | EUR 121.2 |
Woody Plants Medium |
|||
CP040-500 | GenDepot | 50L | EUR 151.2 |
EC MEDIUM, MODIFIED |
|||
E05-108-10kg | Alphabiosciences | 10 kg | EUR 1029.6 |
EC MEDIUM, MODIFIED |
|||
E05-108-2Kg | Alphabiosciences | 2 Kg | EUR 271.2 |
EC MEDIUM, MODIFIED |
|||
E05-108-500g | Alphabiosciences | 500 g | EUR 117.6 |
FLUID THIOGLYCOLLATE MEDIUM |
|||
F06-101-10kg | Alphabiosciences | 10 kg | EUR 950.4 |
FLUID THIOGLYCOLLATE MEDIUM |
|||
F06-101-2kg | Alphabiosciences | 2kg | EUR 253.2 |
FLUID THIOGLYCOLLATE MEDIUM |
|||
F06-101-500g | Alphabiosciences | 500 g | EUR 112.8 |
Recovery Medium - 6x12mL |
|||
1711 | Intact Genomics | 4/PK | EUR 153.6 |
RPMI 1640 Medium |
|||
abx098879-500ml | Abbexa | 500 ml | EUR 210 |
A-1 MEDIUM |
|||
A01-116-10kg | Alphabiosciences | 10 kg | EUR 1240.8 |
A-1 MEDIUM |
|||
A01-116-2Kg | Alphabiosciences | 2 Kg | EUR 316.8 |
A-1 MEDIUM |
|||
A01-116-500g | Alphabiosciences | 500 g | EUR 129.6 |
MOTILITY TEST MEDIUM |
|||
M13-121-10kg | Alphabiosciences | 10 kg | EUR 1833.6 |
MOTILITY TEST MEDIUM |
|||
M13-121-2Kg | Alphabiosciences | 2 Kg | EUR 445.2 |
MOTILITY TEST MEDIUM |
|||
M13-121-500g | Alphabiosciences | 500 g | EUR 164.4 |
OF BASAL MEDIUM |
|||
O15-100-10kg | Alphabiosciences | 10 kg | Ask for price |
OF BASAL MEDIUM |
|||
O15-100-2kg | Alphabiosciences | 2kg | Ask for price |
OF BASAL MEDIUM |
|||
O15-100-500g | Alphabiosciences | 500 g | Ask for price |
Hepatocyte Maintenance Medium |
|||
HM42600 | Neuromics | 100 ml | EUR 490.8 |
Neuron Growth Medium |
|||
HNM001 | Neuromics | 500 ml | EUR 397.2 |
Agarose, medium EEO |
|||
GE4750-100G | Glentham Life Sciences | 100 g | EUR 199.2 |
Agarose, medium EEO |
|||
GE4750-500G | Glentham Life Sciences | 500 g | EUR 514.8 |
REINFORCED CLOSTRIDIUM MEDIUM |
|||
R18-105-10kg | Alphabiosciences | 10 kg | EUR 1432.8 |
REINFORCED CLOSTRIDIUM MEDIUM |
|||
R18-105-2kg | Alphabiosciences | 2kg | EUR 358.8 |
REINFORCED CLOSTRIDIUM MEDIUM |
|||
R18-105-500g | Alphabiosciences | 500 g | EUR 141.6 |
Schwann Growth Medium |
|||
SGM001 | Neuromics | 500 ml | EUR 292.8 |
Sepadextran-25 Medium |
|||
SD25M-100 | ABTBeads | 100 g | EUR 325.2 |
Sepadextran-25 Medium |
|||
SD25M-500 | ABTBeads | 500 g | EUR 1243.2 |
Sepadextran-50 Medium |
|||
SD50M-100 | ABTBeads | 100 g | EUR 412.8 |
Sepadextran-50 Medium |
|||
SD50M-500 | ABTBeads | 500 g | EUR 1542 |
TERRIFIC BROTH MEDIUM |
|||
T20-114-10kg | Alphabiosciences | 10 kg | EUR 810 |
TERRIFIC BROTH MEDIUM |
|||
T20-114-2kg | Alphabiosciences | 2kg | EUR 223.2 |
TERRIFIC BROTH MEDIUM |
|||
T20-114-500g | Alphabiosciences | 500 g | EUR 104.4 |
THIOGLYCOLLATE MEDIUM, BREWER |
|||
T20-118-10kg | Alphabiosciences | 10 kg | EUR 1636.8 |
THIOGLYCOLLATE MEDIUM, BREWER |
|||
T20-118-2kg | Alphabiosciences | 2kg | EUR 403.2 |
THIOGLYCOLLATE MEDIUM, BREWER |
|||
T20-118-500g | Alphabiosciences | 500 g | EUR 153.6 |
2XYT MICROBIAL MEDIUM |
|||
X24-102-10kg | Alphabiosciences | 10 kg | EUR 736.8 |
2XYT MICROBIAL MEDIUM |
|||
X24-102-2Kg | Alphabiosciences | 2 Kg | EUR 207.6 |
2XYT MICROBIAL MEDIUM |
|||
X24-102-500g | Alphabiosciences | 500 g | EUR 99.6 |
Lowenstein-Jensen Medium |
|||
MED1400 | Scientific Laboratory Supplies | EACH | EUR 114 |
Sabouraud Liquid Medium |
|||
MED1462 | Scientific Laboratory Supplies | EACH | EUR 54.61 |
Slanetz & Bartley Medium |
|||
MED1468 | Scientific Laboratory Supplies | EACH | EUR 107.16 |
Dermatophyte Test Medium |
|||
MED1484 | Scientific Laboratory Supplies | EACH | EUR 87.78 |