
dbSNP: databáze NCBI genetických variací.
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dbSNP: databáze NCBI genetických variací.
In response to a necessity for a standard catalog of genome variation to cope with the large-scale sampling designs required by affiliation analysis, gene mapping and evolutionary biology, the Nationwide Coronary heart for Biotechnology Knowledge (NCBI) has established the dbSNP database [S.T.Sherry, M.Ward and K. Sirotkin (1999) Genome Res., 9, 677-679]. Submissions to dbSNP may be built-in with completely different sources of data at NCBI harking back to GenBank, PubMed, LocusLink and the Human Genome Endeavor info.

![]() PI |
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PI | ImmunoStep | 400 test | EUR 154 |
![]() PI/RNAse |
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PI/RNASE | ImmunoStep | 200 test | EUR 173.5 |
![]() 50 ML AMPHOTERICIN B, LIQUID 250 µG/ML SOLUBILIZED |
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30-003-CF | CORNING | 50 mL/pk | EUR 81 |
Description: Media Catalog; Cell Culture Reagents |
![]() 50 ML KANAMYCIN SULFATE, LIQUID, 5,000 µG/ML SOLUTION |
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30-006-CF | CORNING | 50 mL/pk | EUR 98 |
Description: Media Catalog; Cell Culture Reagents |
![]() Amphotericin B (Fungizone) Sol, 250 µg/mL |
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CCM1120-100 | Bio Basic | 100 mL | EUR 110.23 |
![]() Human Proinsulin (PI) ELISA Kit |
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RD-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 478 |
![]() Human Proinsulin (PI) ELISA Kit |
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RD-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 662 |
![]() Porcine Proinsulin (PI) ELISA Kit |
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RD-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 555 |
![]() Porcine Proinsulin (PI) ELISA Kit |
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RD-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 771 |
![]() Human Proinsulin (PI) ELISA Kit |
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DLR-PI-Hu-48T | DL Develop | 48T | EUR 479 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Human Proinsulin (PI) ELISA Kit |
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DLR-PI-Hu-96T | DL Develop | 96T | EUR 621 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Porcine Proinsulin (PI) ELISA Kit |
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DLR-PI-p-48T | DL Develop | 48T | EUR 547 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Porcine Proinsulin (PI) ELISA Kit |
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DLR-PI-p-96T | DL Develop | 96T | EUR 715 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Human Proinsulin (PI) ELISA Kit |
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RDR-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 500 |
![]() Human Proinsulin (PI) ELISA Kit |
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RDR-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 692 |
![]() Porcine Proinsulin (PI) ELISA Kit |
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RDR-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 580 |
![]() Porcine Proinsulin (PI) ELISA Kit |
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RDR-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 807 |
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30-004-CI | CORNING | 100 mL/pk | EUR 103 |
Description: Media Catalog; Cell Culture Reagents |
![]() Latex-in-a-Box Conjugation Kit, Blue 0.3 micron, 7 mL |
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LIB03-B007 | BioAssayWorks | 7 mL | EUR 733.94 |
Description: Latex-in-a-Box Conjugation Kit conjugates blue 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
![]() Latex-in-a-Box Conjugation Kit, Red 0.3 micron, 7 mL |
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LIB03-R007 | BioAssayWorks | 7 mL | EUR 733.94 |
Description: Latex-in-a-Box Conjugation Kit conjugates red 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
![]() Fluorguard Antifade Mounting Medium |
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F001 | Insitus Biotechnologies | 1 ml | EUR 86 |
![]() Penicillin-Streptomycin 100X Solution, 10, 000 Units/mL, 10, 000 µg/mL |
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CCM1133-100 | Bio Basic | 100 mL | EUR 64.05 |
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30-001-CI | CORNING | 100 mL/pk | EUR 82 |
Description: Media Catalog; Cell Culture Reagents |
![]() 100 ML PENICILLIN-STREPTOMYCIN-L-GLUTAMINE, 100X, 10,000 I.U. PENCILLIN (PER ML) 10,000 µG/ML STREPTOMYCIN 29.2 MG/ML L-GLUTAMINE |
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30-009-CI | CORNING | 100 mL/pk | EUR 80 |
Description: Media Catalog; Cell Culture Reagents |
![]() PI |
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abx290031-400tests | Abbexa | 400 tests | EUR 258 |
![]() pI |
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EF007077 | Lifescience Market | 96 Tests | EUR 689 |
![]() Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes (2 x 0.3 mL) |
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0801384 | Zeptometrix | 2 x 0.3 mL | EUR 330.8 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
![]() PI/ Rat PI ELISA Kit |
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ELA-E0379r | Lifescience Market | 96 Tests | EUR 886 |
![]() 0.3 ml 8-Strip Tubes & Domed Caps, 250 Strips of 8 Tubes and Caps |
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GP209 | GenDepot | 2,000 tubes/caps | EUR 334 |
![]() Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA3800 | ScyTek Laboratories | 1 Gal. | EUR 241 |
![]() Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA500 | ScyTek Laboratories | 500 ml | EUR 90 |
![]() Brilliant Cresyl Blue (0.3%, Alcoholic) |
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BCA999 | ScyTek Laboratories | 1000 ml | EUR 116 |
![]() Random Hexamers 100 µg |
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26-4000-03 | Gene Link | 100 ug | EUR 125 |
Description: Random Primers are a mixture of oligonucleotides representing all possible sequence for that size. Random Primers can be used to prime synthesis in oligo-labeling similar to using hexamers (1,2) and cDNA synthesis. Random prime labeling yields high specific activity labeled DNA probe which can be used for all southern, northern and in situ hybridization studies. Random Primers can be also used similar to using hexamers in cDNA synthesis in combination with oligo d(T) to yield more 5' end cDNA sequence. Recently random primers have been used to detect DNA polymorphism. These polymorphisms, simply detected as DNA segments which amplify from one parent but not the other, are inherited in a Mendelian fashion and can be used to construct genetic maps in a variety of species. The authors suggested that these polymorphisms be called RAPD (pronounced RAPID) makers, after Random Amplified Polymorphic DNA (3). References 1. Feinberg, A.P. & Vogelstein, B. (1983) Anal. Biochem. 132:6-13. 2. Feinberg, A.P. & Vogelstein, B. (1984) Anal. Biochem. 137:266-267. 3. Williams J. G., Kubelik A.R., Livak K.J., Rafalski J.A. & Tingey S.V. (1990) Nucleic Acid Res. 18(22):6531-5. |
![]() Rat Monoclonal Anti-Mouse CD4 Pur. Low Endotoxin (Clone YTS 191.1) (rat IgG2b) |
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MCD004-ML | Alpha Diagnostics | 100 ug | EUR 408 |
![]() Rat Monoclonal Anti-Mouse CD25 , Pur. Low Endotoxin (Clone PC61.5.3) (rat IgG1) |
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MCD025-ML | Alpha Diagnostics | 100 ug | EUR 408 |
![]() BrightGreen miRNA qPCR MasterMix-Low ROX |
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MasterMix-mL | ABM | 4 x 1.25 ml for 500 reactions | EUR 151 |
![]() PI-828 |
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HY-108606 | MedChemExpress | 1mg | EUR 142 |
![]() PI-3065 |
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HY-12235 | MedChemExpress | 10mM/1mL | EUR 204 |
![]() PI-1840 |
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HY-12286 | MedChemExpress | 50mg | EUR 587 |
![]() PI-103 |
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HY-10115 | MedChemExpress | 100mg | EUR 546 |
![]() PI-103 |
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E1KS1038 | EnoGene | 5mg | EUR 325 |
![]() PI / RNAse |
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abx290029-200tests | Abbexa | 200 tests | EUR 272 |
![]() PI-3065 |
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B4660-10 | ApexBio | 10 mg | EUR 224 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
![]() PI-3065 |
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B4660-100 | ApexBio | 100 mg | EUR 792 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
![]() PI-3065 |
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B4660-5 | ApexBio | 5 mg | EUR 166 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
![]() PI-3065 |
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B4660-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 177 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
![]() PI-3065 |
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B4660-50 | ApexBio | 50 mg | EUR 572 |
Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
![]() PI-1840 |
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B4755-10 | ApexBio | 10 mg | EUR 184 |
Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
![]() PI-1840 |
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B4755-50 | ApexBio | 50 mg | EUR 522 |
Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
![]() PI-103 |
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A2067-25 | ApexBio | 25 mg | EUR 328 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
![]() PI-103 |
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A2067-5 | ApexBio | 5 mg | EUR 147 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
![]() PI-103 |
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A2067-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 154 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
![]() PI-103 |
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A2067-S | ApexBio | Evaluation Sample | EUR 81 |
Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
![]() PI 828 |
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B7198-1 | ApexBio | 1 mg | EUR 126 |
![]() PI 828 |
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B7198-10 | ApexBio | 10 mg | EUR 318 |
![]() PI 828 |
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B7198-5 | ApexBio | 5 mg | EUR 203 |
![]() PI-3065 |
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B1674-25 | Biovision | EUR 506 |
![]() PI-3065 |
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B1674-5 | Biovision | EUR 158 |
![]() PI-103 |
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1728-1 | Biovision | EUR 153 |
![]() PI-103 |
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1728-5 | Biovision | EUR 419 |
![]() PI-103 |
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1728-50 | Biovision | Ask for price |
![]() Glutathione S-Transferase Pi (GST pi) Antibody |
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abx020559-10ug | Abbexa | 10 ug | EUR 342 |
![]() DiagPoly Amine Polystyrene Particles, 0.3 µm |
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DNM-F002 | Creative Diagnostics | 10 mL | EUR 580 |
![]() Recombinant Proinsulin (PI) |
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4-RPA379Hu01 | Cloud-Clone |
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Description: Recombinant Human Proinsulin expressed in: E.coli |
![]() Pi-Methylimidazoleacetic acid |
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HY-113274 | MedChemExpress | 5mg | EUR 187 |
![]() PI-103 (Hydrochloride) |
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HY-10115A | MedChemExpress | 5mg | EUR 119 |
![]() Human PI Protein |
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20-abx650990 | Abbexa |
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![]() PI Staining Kit |
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abx097208-1Kit | Abbexa | 1 Kit | EUR 230 |
![]() Phosphatidylinositol (PI) Antibody |
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20-abx179006 | Abbexa |
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![]() PI-103 Hydrochloride |
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A3724-100 | ApexBio | 100 mg | EUR 838 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
![]() PI-103 Hydrochloride |
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A3724-25 | ApexBio | 25 mg | EUR 328 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
![]() PI-103 Hydrochloride |
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A3724-5 | ApexBio | 5 mg | EUR 147 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
![]() PI-103 Hydrochloride |
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A3724-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 154 |
Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
![]() PI-8 Antibody |
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3748-100 | Biovision | EUR 316 |
![]() PI-8 Antibody |
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3748-30T | Biovision | EUR 146 |
![]() PI-8 antibody |
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70R-12052 | Fitzgerald | 100 ug | EUR 392 |
Description: Rabbit polyclonal PI-8 antibody |
![]() DAPI, 10mg/mL in H2O |
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40043 | Biotium | 1ML | EUR 134 |
Description: Minimum order quantity: 1 unit of 1ML |
![]() Anti-Pichia pastoris HCP |
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PI-49 | Cygnus Technologies | 1 ml | EUR 334 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
![]() Anti-Pichia pastoris HCP |
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PI-49AF | Cygnus Technologies | 1 mg | EUR 1913 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
![]() Anti-Pichia pastoris HCP |
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PI-49PA | Cygnus Technologies | 1 ml | EUR 488 |
Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
![]() DiagPoly Plain Polystyrene Particles, 0.2-0.3 µm |
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DNM-P003 | Creative Diagnostics | 10 mL | EUR 554 |
![]() Rabbit Anti-Rat Glutathione Transferees pi (GST-pi) antiserum |
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GSTP11-S | Alpha Diagnostics | 100 ul | EUR 457 |
![]() Rabbit Anti-Human Glutathione Transferase Pi (GST-pi) antiserum |
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GSTP12-S | Alpha Diagnostics | 100 ul | EUR 457 |
![]() Anti-PON1 Clone KRJ1 (100 µg) |
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0801012 | Zeptometrix | 100 µg | EUR 284 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
![]() Anti-PON1 Clone KRJ2 (100 µg) |
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0801014 | Zeptometrix | 100 µg | EUR 284 |
Description: Please contact Gentaur in order to receive the datasheet of the product. |
![]() bFGF-nAb Purified Protein 25 µg |
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ABP-NAB-BFGFAB | Allele Biotech | 25 µg | Ask for price |
![]() bFGF-nAb Plus Biotinylated 25 µg |
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ABP-NAB-BFGFPB | Allele Biotech | 25 µg | Ask for price |
![]() GFP-nAb Purified Protein 25 µg |
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ABP-NAB-GFPAB | Allele Biotech | 25 µg | Ask for price |
![]() GFP-nAb Plus Biotinylated 25 µg |
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ABP-NAB-GFPPB | Allele Biotech | 25 µg | Ask for price |
![]() mNeonGreen-nAb Purified Protein 25 µg |
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ABP-NAB-MNGAB | Allele Biotech | 25 µg | Ask for price |
![]() mNeonGreen-nAb Plus Biotinylated 25 µg |
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ABP-NAB-MNGPB | Allele Biotech | 25 µg | Ask for price |
![]() RFP-nAb Purified Protein 25 µg |
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ABP-NAB-RFPAB | Allele Biotech | 25 ug | Ask for price |
![]() RFP-nAb Plus Biotinylated 25 µg |
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ABP-NAB-RFPPB | Allele Biotech | 25 µg | Ask for price |
![]() Ethidium bromide, 10mg/ml in water |
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GT9211-10ML | Glentham Life Sciences | 10 ml | EUR 70 |
![]() Papain Solution In PBS, 1mg/ml |
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CA093-002 | GenDepot | 20ml | Ask for price |
![]() Acridine Orange, 10mg/mL in water |
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40039 | Biotium | 10ML | EUR 101 |
Description: Minimum order quantity: 1 unit of 10ML |
Vylepšené monomerní červené, oranžové a žluté fluorescenční proteiny odvozené od Discosoma sp. červený fluorescenční protein.
Fluorescent proteins are genetically encoded, merely imaged reporters important in biology and biotechnology. When a protein is tagged by fusion to a fluorescent protein, interactions between fluorescent proteins can undesirably disturb specializing in or function. Sadly, all wild-type yellow-to-red fluorescent proteins reported to this point are obligately tetrameric and typically toxic or disruptive. The first true monomer was mRFP1, derived from the Discosoma sp. fluorescent protein “DsRed” by directed evolution first to increase the tempo of maturation, then to interrupt each subunit interface whereas restoring fluorescence, which cumulatively required 33 substitutions.
Although mRFP1 has already confirmed broadly useful, various properties may bear enchancment and further colors may very well be welcome. We report the next period of monomers. The latest crimson mannequin matures additional absolutely, is additional tolerant of N-terminal fusions and is over tenfold additional photostable than mRFP1. Three monomers with distinguishable hues from yellow-orange to red-orange have bigger quantum efficiencies.
Chamtivý algoritmus skilled srovnávání sekvencí DNA.
For aligning DNA sequences that differ solely by sequencing errors, or by equal errors from completely different sources, a greedy algorithm could also be quite a bit before standard dynamic programming approaches and however produce an alignment that is assured to be theoretically optimum. We introduce a model new greedy alignment algorithm with notably good effectivity and current that it computes the an identical alignment as does a certain dynamic programming algorithm, whereas executing over 10 cases sooner on relevant info. An implementation of this algorithm is presently utilized in a program that assembles the UniGene database on the Nationwide Coronary heart for Biotechnology Knowledge.
Vývoj a aplikace CRISPR-Cas9 skilled genomové inženýrství.
Newest advances in genome engineering utilized sciences based totally on the CRISPR-associated RNA-guided endonuclease Cas9 are enabling the systematic interrogation of mammalian genome function. Analogous to the search function in fashionable phrase processors, Cas9 could also be guided to explicit areas inside sophisticated genomes by a short RNA search string. Using this system, DNA sequences all through the endogenous genome and their purposeful outputs in the meanwhile are merely edited or modulated in practically any organism of different.
Cas9-mediated genetic perturbation is straightforward and scalable, empowering researchers to elucidate the purposeful group of the genome on the methods diploma and arrange causal linkages between genetic variations and natural phenotypes. On this Consider, we describe the occasion and features of Cas9 for a variety of study or translational features whereas highlighting challenges along with future directions. Derived from a excellent microbial safety system, Cas9 is driving progressive features from basic biology to biotechnology and medicines.
Vylepšená Greengenesova taxonomie s explicitními hodnotami skilled ekologické a evoluční analýzy bakterií a archea.
- Reference phylogenies are important for providing a taxonomic framework for interpretation of marker gene and metagenomic surveys, which proceed to reveal novel species at a excellent cost. Greengenes is a loyal full-length 16S rRNA gene database that provides prospects with a curated taxonomy based totally on de novo tree inference.
- We developed a ‘taxonomy to tree’ methodology for transferring group names from an present taxonomy to a tree topology, and used it to make use of the Greengenes, Nationwide Coronary heart for Biotechnology Knowledge (NCBI) and cyanoDB (Cyanobacteria solely) taxonomies to a de novo tree comprising 408,315 sequences. We moreover included categorical rank information provided by the NCBI taxonomy to group names (by prefixing rank designations) for greater particular person orientation and classification consistency.
- The following merged taxonomy improved the classification of 75% of the sequences by various ranks relative to the distinctive NCBI taxonomy with the most pronounced enhancements occurring in under-classified environmental sequences. We moreover assessed candidate phyla (divisions) presently outlined by NCBI and present solutions for consolidation of 34 redundantly named groups.
- All intermediate outcomes from the pipeline, which contains tree inference, jackknifing and swap of a donor taxonomy to a recipient tree (tax2tree) could be discovered for get hold of. The improved Greengenes taxonomy must current very important infrastructure for a wide range of megasequencing initiatives discovering out ecosystems on scales ranging from our private our our bodies (the Human Microbiome Endeavor) to the whole planet (the Earth Microbiome Endeavor).
Molekulární chaperony v cytosolu: od rodícího se řetězce po skládaný protein.
Setting pleasant folding of many newly synthesized proteins relies upon upon assist from molecular chaperones, which serve to cease protein misfolding and aggregation inside the crowded ambiance of the cell. Nascent chain–binding chaperones, along with set off situation, Hsp70, and prefoldin, stabilize elongating chains on ribosomes in a nonaggregated state.
Folding inside the cytosol is achieved each on managed chain launch from these components or after swap of newly synthesized proteins to downstream chaperones, such as a result of the chaperonins. These are large, cylindrical complexes that current a central compartment for a single protein chain to fold unimpaired by aggregation. Understanding how the 1000’s of varied proteins synthesized in a cell use this chaperone tools has profound implications for biotechnology and medicines.
Konstrukce genetického přepínače v Escherichia coli.
It has been proposed’ that gene-regulatory circuits with practically any desired property could also be constructed from networks of easy regulatory components. These properties, which embody multistability and oscillations, have been current in specialised gene circuits such as a result of the bacteriophage lambda change and the Cyanobacteria circadian oscillator. However, these behaviours have not been demonstrated in networks of non-specialized regulatory components. Proper right here we present the event of a genetic toggle switch-a synthetic, bistable gene-regulatory network-in Escherichia coli and provide a straightforward precept that predicts the circumstances compulsory for bistability.
The toggle is constructed from any two repressible promoters organized in a mutually inhibitory neighborhood. It is flipped between regular states using transient chemical or thermal induction and shows an virtually supreme switching threshold. As a wise system, the toggle change sorts a synthetic, addressable cellular memory unit and has implications for biotechnology, biocomputing and gene treatment.
![]() FluoreGuard Mounting Medium |
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FMM999 | ScyTek Laboratories | 1000 ml | EUR 530 |
![]() SuperMOUNT? Mounting Medium |
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1211-20 | Biovision | EUR 201 |
![]() Fluorguard Antifade Mounting Medium |
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F001 | Insitus Biotechnologies | 1 ml | EUR 86 |
![]() Anti-Fade Mounting Medium |
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abx090692-10ml | Abbexa | 10 ml | EUR 203 |
![]() EverBrite Hardset Mounting Medium |
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23003 | Biotium | 10mL | EUR 195 |
Description: Minimum order quantity: 1 unit of 10mL |
![]() EverBrite Mounting Medium with DAPI |
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23002 | Biotium | 10mL | EUR 195 |
Description: Minimum order quantity: 1 unit of 10mL |
![]() FluoreGuard Mounting Medium (Hard Set) |
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FMH030 | ScyTek Laboratories | 30 ml | EUR 96 |
![]() FluoreGuard Mounting Medium (Hard Set) |
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FMH060 | ScyTek Laboratories | 60 ml | EUR 116 |
![]() FluoreGuard Mounting Medium (Hard Set) |
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FMH500 | ScyTek Laboratories | 500 ml | EUR 327 |
![]() FluoreGuard Mounting Medium (Hard Set) |
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FMH999 | ScyTek Laboratories | 1000 ml | EUR 530 |
![]() Anti-Fade Mounting Medium (With DAPI) |
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abx090690-10ml | Abbexa | 10 ml | EUR 203 |
![]() Anti-Fade Mounting Medium (With PI) |
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abx090691-10ml | Abbexa | 10 ml | EUR 203 |
![]() EverBrite Hardset Mounting Medium with DAPI |
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23004 | Biotium | 10mL | EUR 213 |
Description: Minimum order quantity: 1 unit of 10mL |
![]() FluoroQuest™ Mounting Medium with DAPI |
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20004 | AAT Bioquest | 50 mL | EUR 132 |
![]() Mounting Media |
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99-MED | Fitzgerald | 3 ml | EUR 211 |
Description: Mounting media for use in microscopy preparations |
![]() FluorLast? Mounting Media |
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1213-20 | Biovision | EUR 142 |
![]() Permanent Mounting Media (Aqueous) |
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PMT030 | ScyTek Laboratories | 30 ml | EUR 109 |
![]() Permanent Mounting Media (Aqueous) |
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PMT999 | ScyTek Laboratories | 1000 ml | EUR 759 |
![]() Buffered Glycerol Mounting Media |
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GMM003 | ScyTek Laboratories | 3 ml | EUR 61 |
![]() Buffered Glycerol Mounting Media |
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GMM030 | ScyTek Laboratories | 30 ml | EUR 72 |
![]() Buffered Glycerol Mounting Media |
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GMM500 | ScyTek Laboratories | 500 ml | EUR 183 |
![]() Buffered Glycerol Mounting Media |
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GMM999 | ScyTek Laboratories | 1000 ml | EUR 260 |
![]() ReadiUse™ microscope mounting solution |
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20009 | AAT Bioquest | 50 mL | EUR 115 |
![]() Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 60ml |
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NB300 | Innovex | 60 ml | EUR 427 |
![]() Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 30ml |
|||
NB300-30 | Innovex | 30 ml | EUR 276 |
![]() Advantage Mounting Media, for permanent mounting and Coverslipping IHC & special stains from water, 125ml |
|||
NB300A | Innovex | 125 ml | EUR 543 |
![]() PolyMount Mounting Media MaxTag Histo (OKRA00045) |
|||
OKRA00045 | Aviva Systems Biology | 15 ml | EUR 126 |
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity: |
![]() Fine natural hair brush for mounting sections |
|||
PO501 | FD Neurotechnologies | each | EUR 67 |
![]() A Medium |
|||
DJ1018 | Bio Basic | 100g | EUR 84.8 |
![]() Advanced Medium |
|||
C0003-04 | Addexbio | RT 500 mL Bottle | EUR 103 |
![]() Medium 199 |
|||
C0012-01 | Addexbio | RT 500 mL Bottle | EUR 105 |
![]() Heller's Medium |
|||
CP014-010 | GenDepot | 10X1L | EUR 99 |
![]() Heller's Medium |
|||
CP014-500 | GenDepot | 50L | EUR 126 |
![]() Hoagland's Medium |
|||
CP015-010 | GenDepot | 10X1L | EUR 99 |
![]() Hoagland's Medium |
|||
CP015-500 | GenDepot | 50L | EUR 126 |
![]() M9 Medium |
|||
SD7024 | Bio Basic | 250g | EUR 71.75 |
![]() M9CA Medium |
|||
SD7025 | Bio Basic | 250g | EUR 71.75 |
![]() YM Medium |
|||
SD7031 | Bio Basic | 250g | EUR 70.45 |
![]() TYGPN Medium |
|||
SD7032 | Bio Basic | 250g | EUR 70.01 |
![]() M63 Medium |
|||
SD7033 | Bio Basic | 250g | EUR 71.75 |
![]() NeuroProgenitor Medium |
|||
NM42400 | Neuromics | 125 ml | EUR 304 |
![]() COLIFORM MEDIUM |
|||
C03-127-10kg | Alphabiosciences | 10 kg | EUR 1324 |
![]() COLIFORM MEDIUM |
|||
C03-127-2kg | Alphabiosciences | 2kg | EUR 327 |
![]() COLIFORM MEDIUM |
|||
C03-127-500g | Alphabiosciences | 500 g | EUR 125 |
![]() HLP MEDIUM |
|||
H08-107-10kg | Alphabiosciences | 10 kg | EUR 2278 |
![]() HLP MEDIUM |
|||
H08-107-2Kg | Alphabiosciences | 2 Kg | EUR 534 |
![]() HLP MEDIUM |
|||
H08-107-500g | Alphabiosciences | 500 g | EUR 182 |
![]() EC MEDIUM |
|||
E05-100-10kg | Alphabiosciences | 10 kg | EUR 814 |
![]() EC MEDIUM |
|||
E05-100-2Kg | Alphabiosciences | 2 Kg | EUR 216 |
![]() EC MEDIUM |
|||
E05-100-500g | Alphabiosciences | 500 g | EUR 95 |
![]() DC MEDIUM |
|||
D04-117-10kg | Alphabiosciences | 10 kg | EUR 1579 |
![]() DC MEDIUM |
|||
D04-117-2kg | Alphabiosciences | 2kg | EUR 382 |
![]() DC MEDIUM |
|||
D04-117-500g | Alphabiosciences | 500 g | EUR 140 |
![]() SIM MEDIUM |
|||
S19-110-10kg | Alphabiosciences | 10 kg | EUR 1021 |
![]() SIM MEDIUM |
|||
S19-110-2kg | Alphabiosciences | 2kg | EUR 261 |
![]() SIM MEDIUM |
|||
S19-110-500g | Alphabiosciences | 500 g | EUR 107 |
![]() SOB MEDIUM |
|||
S19-124-10kg | Alphabiosciences | 10 kg | EUR 965 |
![]() SOB MEDIUM |
|||
S19-124-2kg | Alphabiosciences | 2kg | EUR 249 |
![]() SOB MEDIUM |
|||
S19-124-500g | Alphabiosciences | 500 g | EUR 104 |
![]() Probe Mount, Permanent Mounting media for permanent mounting and coverslipping of Special stainsd & Immunofluorescence and In-Situ Stains 60ml |
|||
NB316 | Innovex | 60 ml | EUR 485 |
![]() Insect Cell Medium: TNM-FH Insect Culture Medium |
|||
ABP-MED-10001 | Allele Biotech | 1 liter | Ask for price |
![]() Insect Cell Medium: Serum-Free Insect Culture Medium |
|||
ABP-MED-10002 | Allele Biotech | 1 liter | Ask for price |
![]() Insect Cell Medium: Grace?s Insect Medium (Unsupplemented) |
|||
ABP-MED-10004 | Allele Biotech | 1 liter | Ask for price |
![]() H Medium Broth |
|||
DJ1019 | Bio Basic | 100g | EUR 60.88 |
![]() AddexBio Cryopreservation Medium |
|||
C0002-20mL | Addexbio | RT vial | EUR 104 |
![]() RPMI 1640 Medium |
|||
abx098879-500ml | Abbexa | 500 ml | EUR 175 |
![]() Recovery Medium - 6x12mL |
|||
1711 | Intact Genomics | 4/PK | EUR 128 |
![]() Agarose, medium EEO |
|||
GE4750-100G | Glentham Life Sciences | 100 g | EUR 166 |
![]() Agarose, medium EEO |
|||
GE4750-500G | Glentham Life Sciences | 500 g | EUR 429 |
![]() Schwann Growth Medium |
|||
SGM001 | Neuromics | 500 ml | EUR 244 |
![]() MCDB 131 Medium |
|||
CM034-050 | GenDepot | 500ml | EUR 85 |
![]() MCDB 131 Medium |
|||
CM034-300 | GenDepot | 6x500ml | EUR 165 |
![]() MCDB 131 Medium |
|||
CM034-310 | GenDepot | 10x500ml | EUR 219 |
![]() MCDB 131 Medium |
|||
CM034-320 | GenDepot | 20x500ml | EUR 340 |
![]() MCDB 131 Medium |
|||
CM034-350 | GenDepot | 50x500ml | EUR 585 |
![]() Williams' Medium E |
|||
CM063-050 | GenDepot | 500ml | EUR 91 |
![]() Williams' Medium E |
|||
CM063-300 | GenDepot | 6x500ml | EUR 266 |
![]() Williams' Medium E |
|||
CM063-310 | GenDepot | 10x500ml | EUR 313 |
![]() Williams' Medium E |
|||
CM063-320 | GenDepot | 20x500ml | EUR 604 |
![]() Williams' Medium E |
|||
CM063-350 | GenDepot | 50x500ml | EUR 975 |
![]() Cereal Crops Medium |
|||
CP003-005 | GenDepot | 5L | EUR 113 |
![]() Cereal Crops Medium |
|||
CP003-010 | GenDepot | 10X1L | EUR 169 |
![]() Kao Michayluk Medium |
|||
CP017-010 | GenDepot | 10X1L | EUR 99 |
![]() Kao Michayluk Medium |
|||
CP017-500 | GenDepot | 50L | EUR 126 |
![]() Orchid Maintenance Medium |
|||
CP037-010 | GenDepot | 10X1L | EUR 109 |
![]() Orchid Maintenance Medium |
|||
CP037-500 | GenDepot | 50L | EUR 138 |
![]() Woody Plants Medium |
|||
CP040-010 | GenDepot | 10X1L | EUR 101 |
![]() Woody Plants Medium |
|||
CP040-500 | GenDepot | 50L | EUR 126 |
![]() Hepatocyte Maintenance Medium |
|||
HM42600 | Neuromics | 100 ml | EUR 409 |
![]() Neuron Growth Medium |
|||
HNM001 | Neuromics | 500 ml | EUR 331 |
![]() CARY & BLAIR MEDIUM |
|||
C03-131-10kg | Alphabiosciences | 10 kg | EUR 2185 |
![]() CARY & BLAIR MEDIUM |
|||
C03-131-2Kg | Alphabiosciences | 2 Kg | EUR 514 |
![]() CARY & BLAIR MEDIUM |
|||
C03-131-500g | Alphabiosciences | 500 g | EUR 176 |
![]() FLUID THIOGLYCOLLATE MEDIUM |
|||
F06-101-10kg | Alphabiosciences | 10 kg | EUR 792 |