• April 29, 2021
alidea

dbSNP: databáze NCBI genetických variací.

dbSNP: databáze NCBI genetických variací.  In response to a necessity for a standard catalog of genome variation to cope with the large-scale sampling designs required by affiliation analysis, gene mapping and evolutionary biology, the Nationwide Coronary heart for Biotechnology Knowledge (NCBI) has established the dbSNP database [S.T.Sherry, M.Ward and K. Sirotkin (1999) Genome Res., 9, 677-679].…

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alidea

Revidovaná kritéria odpovědi pro maligní lymfom

Revidovaná kritéria odpovědi professional maligní lymfom. Standardized response standards are wanted to interpret and examine medical trials and for approval of recent therapeutic brokers by regulatory businesses. METHODS The Worldwide Working Group response standards (Cheson et al, J Clin Oncol 17:1244, 1999) had been extensively adopted, however required reassessment due to recognized limitations and the…

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Anti-ACE2 Antibody

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its ACE counterpart, ACE2 expression is restricted to the heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor for the SARS coronavirus. The normal function of ACE2 is to convert the inactive…

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Vemurafenib

In a phase I clinical study, vemurafenib (then known as PLX4032) was able to reduce the number of cancer cells in more than half of a group of 16 patients with advanced melanoma. The treated group had a median increase in survival time of 6 months compared to the control group. [15] [16] [17] [18]…

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GENTAUR

An update was made on Alzheimer’s disease, which is the most common cause of dementia. Aspects related to chromosomes 21 and 17. Mutations in the amyloid precursor protein gene, located on chromosome 21, are responsible for 5 to 20% of cases of early familial Alzheimer’s disease. The amyloid precursor protein, when processed by an amyloidogenic pathway,…

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