• June 27, 2021
alidea

Integrované polovodičové zařízení umožňující

Integrované polovodičové zařízení umožňující neoptické sekvenování genomu.  The seminal significance of DNA sequencing to the life sciences, biotechnology and drugs has pushed the seek for extra scalable and lower-cost options. Right here we describe a DNA sequencing know-how during which scalable, low-cost semiconductor manufacturing methods are used to make an built-in circuit capable of straight carry out…

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RefSeq: aktualizace referenčních sekvencí savců

RefSeq: aktualizace referenčních sekvencí savců.  The Nationwide Heart for Biotechnology Data (NCBI) Reference Sequence (RefSeq) database is a group of annotated genomic, transcript and protein sequence information derived from knowledge in public sequence archives and from computation, curation and collaboration (http://www.ncbi.nlm.nih.gov/refseq/). We report right here on progress of the mammalian and human subsets, modifications to NCBI’s eukaryotic…

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Abirateron u metastazujícího karcinomu prostaty

Abirateron u metastazujícího karcinomu prostaty bez předchozí chemoterapie. Abiraterone acetate, an androgen biosynthesis inhibitor, improves total survival in sufferers with metastatic castration-resistant prostate most cancers after chemotherapy. We evaluated this agent in sufferers who had not acquired earlier chemotherapy. METHODS On this double-blind examine, we randomly assigned 1088 sufferers to obtain abiraterone acetate (1000 mg)…

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NCBI Reference Sequence (RefSeq):

NCBI Reference Sequence (RefSeq): upravená neredundantní databáze sekvencí genomů, transkriptů a proteinů.  The Nationwide Heart for Biotechnology Info (NCBI) Reference Sequence (RefSeq) database (http://www.ncbi.nlm.nih.gov/RefSeq/) gives a non-redundant assortment of sequences representing genomic information, transcripts and proteins. Though the objective is to supply a complete dataset representing the whole sequence data for any given species, the database pragmatically…

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dbSNP: databáze NCBI genetických variací.

dbSNP: databáze NCBI genetických variací.  In response to a necessity for a standard catalog of genome variation to cope with the large-scale sampling designs required by affiliation analysis, gene mapping and evolutionary biology, the Nationwide Coronary heart for Biotechnology Knowledge (NCBI) has established the dbSNP database [S.T.Sherry, M.Ward and K. Sirotkin (1999) Genome Res., 9, 677-679].…

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alidea

Revidovaná kritéria odpovědi pro maligní lymfom

Revidovaná kritéria odpovědi professional maligní lymfom. Standardized response standards are wanted to interpret and examine medical trials and for approval of recent therapeutic brokers by regulatory businesses. METHODS The Worldwide Working Group response standards (Cheson et al, J Clin Oncol 17:1244, 1999) had been extensively adopted, however required reassessment due to recognized limitations and the…

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Anti-ACE2 Antibody

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its ACE counterpart, ACE2 expression is restricted to the heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor for the SARS coronavirus. The normal function of ACE2 is to convert the inactive…

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Vemurafenib

In a phase I clinical study, vemurafenib (then known as PLX4032) was able to reduce the number of cancer cells in more than half of a group of 16 patients with advanced melanoma. The treated group had a median increase in survival time of 6 months compared to the control group. [15] [16] [17] [18]…

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GENTAUR

An update was made on Alzheimer’s disease, which is the most common cause of dementia. Aspects related to chromosomes 21 and 17. Mutations in the amyloid precursor protein gene, located on chromosome 21, are responsible for 5 to 20% of cases of early familial Alzheimer’s disease. The amyloid precursor protein, when processed by an amyloidogenic pathway,…

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